3.6 Pentastar Misfire on Cylinders 1, 3, & 5

[Threepointsix]

Talk about resurrecting an old thread. Holy crap! If I was OP, I would've given up halfway through that insane and costly process, and sold it.

@Roam8 lucky you, you got yours solved.

 

[Roam8]

Given the description of the issue and the solution provided, I think a vacuum leak under the intake is a great possibility, but how would that have caused all 3 cylinders to be so lean instead of only 1 of them?
Was there any evidence of a failed seal (pinched, damaged, etc.) on the injectors?

Just trying to picture where the failure was that could have affected all 3 cylinders.

To much unburnt oxygen passing the Bank's O2 Sensor will have the PCM enriching the mix on all cylinders... doesnt matter if the source of O2 is a single cylinder or all 3...

I can't say either way because we didn't replace them one at a time...

Our lead shotgunned 3 new injectors on a whim and it worked like a charm..

So I was just passing the info along... Especially since swapping injector banks is not something OP had tried ..